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CATPB is a human FFA2 inverse agonist (pKi = 7.87). It increases forskolin-induced cAMP production, and inhibits acetate-induced MAPK signaling in cells expressing human FFA2.
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Product descriptionCATPB is a potent, selective free fatty acid receptor 2 (FFA2R/GPR43) antagonist.
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Image Search Results
Journal: Frontiers in Cellular and Infection Microbiology
Article Title: Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids
doi: 10.3389/fcimb.2020.620681
Figure Lengend Snippet: Agonists and antagonists, directed towards G-protein coupled receptors (GPCRs), used to stimulate and inhibit neutrophil intracellular Ca 2+ signals.
Article Snippet: GPR43 , Acetate (Merck) , 10 6 ,
Techniques: